Humanised CAR Tregs are a key step forward

TxCell has announced it has a promising humanised CAR-Treg product that can be developed to control graft rejection in solid organ transplant. A trial is planned to start in late 2018. CAR Tregs offer a powerful and versatile new approach to immune system disorders; multiple sclerosis, lupus nephritis and the skin disorder bullous pemphigoid are also targets. TxCell had cash of €8.68m on 30 June. The indicative market cap has been rebased onto CAR Treg indications and is now €84.4m, formerly €74m.