Healthcare equity analyst - emerging & dev mkts, daaimon

Avien Pillay

Healthcare equity analyst - emerging & dev mkts

daaimon

daaimon is an independent research company focusing on healthcare and consumer sectors across developed and emerging markets. We produce insightful research which challenges conventional thinking. In particular, we look for new ideas by testing consensus forecasts and markets expectations.

Equity Bottom-Up

<ul>
<li>Given the high number of pipeline dropouts, and the potentially disappointing $6 bn psoriasis drug acquisition, we question Takeda’s recent investment track record.</li>
<li>A big restructuring, high expectations from new/recently launched drug portfolio, and punchy company guidance reduces the probability of upside surprises.</li>
<li>Unless you are limited from investing outside Japan and you want exposure to an innovative pharma company, we believe that there are better and cheaper options elsewhere.</li>
</ul>


Given the high number of pipeline dropouts, and the potentially disappointing $6 bn psoriasis drug acquisition, we question Takeda’s recent investment track record.
A big restructuring, high expectations from new/recently launched drug portfolio, and punchy company guidance reduces the probability of upside surprises.
Unless you are limited from investing outside Japan and you want exposure to an innovative pharma company, we believe that there are better and cheaper options elsewhere.


HK/China Healthcare Analyst (ex-Fosun Pharma)

Xinyao (Criss) Wang

Ascentage Pharma Group Corp / Equity Bottom-Up

<ul>
<li>Ascentage was originally in an extremely difficult situation, but the cooperation with Takeda turned things around. Ascentage has obtained urgently needed cash flow to solve the survival problem.</li>
<li>At this stage, it’s possible for Ascentage to hit about 50% market value of HCM.  Investors are interested to know if APG-2575 would also be out-licensed, which however is not easy.</li>
<li>Ascentage’s current strength isn’t sufficient to self-build sales system. While this deal is a good start, if Ascentage still chooses to do commercialization on its own, it’s time to sell. </li>
</ul>


Ascentage was originally in an extremely difficult situation, but the cooperation with Takeda turned things around. Ascentage has obtained urgently needed cash flow to solve the survival problem.
At this stage, it’s possible for Ascentage to hit about 50% market value of HCM.  Investors are interested to know if APG-2575 would also be out-licensed, which however is not easy.
Ascentage’s current strength isn’t sufficient to self-build sales system. While this deal is a good start, if Ascentage still chooses to do commercialization on its own, it’s time to sell. 


Ascentage Pharma (6855.HK) Signs $1.3B Deal with Takeda - Finally on the Right Path

Equity Analyst, LightStream Research

Shifara Samsudeen, ACMA, CGMA

Equity Analyst

Long-Short Analysis on Japan, Asia and the World

LightStream Research

LightStream conducts quantitatively rigorous and data-driven analysis with a focus on Japan and Asia.

We consistently cover the Tech, Consumer and Industrial sectors, and provide ECM and Events coverage more broadly.

We supplement traditional qualitative insights from company relationships with a robust quantitative foundation that examines as much historical data as is available.
We further refine the accuracy of our insights and calls through the use of alternative data to flesh out current trends, and through a valuation framework that emphasises non-superficial peer group selection and a proper attempt to understand the metrics and changes that have driven security valuations in the past.

<ul>
<li>Takeda’s 2QFY03/2024 revenues increased 4.1% YoY beating consensus estimates by 6%. However, Takeda reported an operating loss of ¥49.3bn for the quarter due to impairment losses.</li>
<li>As we expected, recent setback in some of Takeda’s clinical trials have led to write-downs and triggered a downward revision to full-year profit guidance.</li>
<li>There has been excessive price reaction to these setbacks, however, Takeda continues to progress with its pipeline development with some newly launched drugs showing great potential.</li>
</ul>


Takeda’s 2QFY03/2024 revenues increased 4.1% YoY beating consensus estimates by 6%. However, Takeda reported an operating loss of ¥49.3bn for the quarter due to impairment losses.
As we expected, recent setback in some of Takeda’s clinical trials have led to write-downs and triggered a downward revision to full-year profit guidance.
There has been excessive price reaction to these setbacks, however, Takeda continues to progress with its pipeline development with some newly launched drugs showing great potential.


Takeda: Guidance Lowered Due to Setbacks in Clinical Trials but Pipeline Development Continues

<ul>
<li>
<a href="https://www.smartkarma.com/entities/takeda-pharmaceutical-co-ltd" target="_blank" data-smartkarma-citation="entities:11747:1" rel="noopener">Takeda Pharmaceutical (4502 JP)</a> reported 1QFY03/2024 results today. Revenue increased 8.9% YoY to ¥1,058.6bn (vs consensus ¥989.8bn) while OP increased 12.0% YoY to ¥168.6bn (vs consensus ¥123.5bn).</li>
<li>The topline growth was driven by growth &amp; launch products which accounted for 40% of total revenues, and increased 16.2% YoY during the quarter at constant exchange rates.</li>
<li>Takeda is expecting 7-8 key regulatory decisions during the current fiscal year and we expect dengue vaccine and other new launches to help offset revenue loss from upcoming patent expiry.</li>
</ul>



Takeda Pharmaceutical (4502 JP) reported 1QFY03/2024 results today. Revenue increased 8.9% YoY to ¥1,058.6bn (vs consensus ¥989.8bn) while OP increased 12.0% YoY to ¥168.6bn (vs consensus ¥123.5bn).
The topline growth was driven by growth &amp; launch products which accounted for 40% of total revenues, and increased 16.2% YoY during the quarter at constant exchange rates.
Takeda is expecting 7-8 key regulatory decisions during the current fiscal year and we expect dengue vaccine and other new launches to help offset revenue loss from upcoming patent expiry.


Takeda: Earnings Beat Driven by Key Drugs and Dengue Vaccine Seeing Positive Momentum

Independent research on the U.S. markets, Baptista Research

Baptista Research

Independent research on the U.S. markets

Baptista Research is an independent financial research house focused on the U.S. markets. We provide equity research as well as credit research reports on the top-listed U.S. companies with most of our focus on technology, consumer goods and services, automobiles, industrials, oil and gas, pharma, and healthcare. Our research has served more than 3000 institutional investors including mutual funds, hedge funds, banks, family offices, and various buy-side firms. We operate a research subscription service where institutions, as well as retail investors, can have priority access to all our research. We also have a wide distribution of our research reports across some of the top global financial platforms. Apart from equity research and credit research, we also provide advisory services with respect to mergers & acquisitions (M&A), private equity/ venture capital fundraising, valuation reports, and investment management services for corporates.
Baptista Research is owned and managed by Ishan Majumdar, an ex-Venture Capitalist/ Investment Banker, a Chartered Accountant, and a Masters’ degree holder in Management from HEC Paris. Ishan has nearly a decade of experience in Mergers and Acquisitions, Leveraged Buyouts (LBOs), Venture Capital Investing, Corporate Strategy, and Valuation in front-office roles at the likes of BNP Paribas CIB, Credit Agricole CIB, Groupe Danone, and TIW Private Equity. He has worked on and closed multiple acquisition deals, leveraged buyouts, and start-up investment transactions.

<ul><li>Takeda delivered a mixed set of results for the previous quarter, with revenues below the analyst consensus.</li><li>Takeda also achieved strong financial performance, exceeding revenue and profit growth expectations.</li><li>We give Takeda Pharmaceutical Company Limited a 'Hold' rating with a revised target price.</li></ul>

Takeda delivered a mixed set of results for the previous quarter, with revenues below the analyst consensus.Takeda also achieved strong financial performance, exceeding revenue and profit growth expectations.We give Takeda Pharmaceutical Company Limited a 'Hold' rating with a revised target price.

Takeda Pharmaceuticals: Does It Have A Sustainable Competitive Advantage? – Key Drivers

Japan

Takeda Pharmaceutical Co Ltd focuses on the Research & Development, Manufacturing, Sales and Marketing and Import/Export of Pharmaceutical Drugs. The Company focuses on the following core therapeutic areas: Cardiovascular & Metabolic, Oncology, Central Nervous System, Respiratory & Immunology, General Medicine (Gastrointestinal & Genitourinary) and Vaccine.

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Takeda Pharmaceutical (4502 JP)

Takeda (4502 JP)– Avoid

A potentially disappointing $6bn acquisition, high pipeline dropout, and limited probability of upside surprises sums up our analysis of expensive...

Avien Pillay

Ascentage Pharma (6855.HK) Signs $1.3B Deal with Takeda - Finally on the Right Path

Cooperation with Takeda saves Ascentage from survival problem, but self-building sales team remains a challenge. Investors eye anther deal with...

Xinyao (Criss) Wang

Takeda: Guidance Lowered Due to Setbacks in Clinical Trials but Pipeline Development Continues

As we have highlighted, Takeda continues to make good progress with its development pipeline where the company has received FDA approval for...

Shifara Samsudeen, ACMA, CGMA

Takeda: Earnings Beat Driven by Key Drugs and Dengue Vaccine Seeing Positive Momentum

Takeda's 1QFY24 earnings beat consensus driven by growth & launch products. Newly launched dengue vaccine has started generating revenues with new...

Shifara Samsudeen, ACMA, CGMA

Takeda Pharmaceuticals: Does It Have A Sustainable Competitive Advantage? – Key Drivers

Takeda delivered a mixed set of results for the previous quarter, with revenues below the analyst consensus. Takeda also achieved strong financial...

Baptista Research

Price Gauge

52-week Range

Market Cap (USDm)

P/E

Dividend (Yield)

Takeda (4502 JP)– Avoid

A potentially disappointing $6bn acquisition, high pipeline dropout, and limited probability of upside surprises sums up our analysis of expensive...

Avien Pillay

Ascentage Pharma (6855.HK) Signs $1.3B Deal with Takeda - Finally on the Right Path

​Cooperation with Takeda saves Ascentage from survival problem, but self-building sales team remains a challenge. Investors eye anther deal with...

Xinyao (Criss) Wang

Takeda: Guidance Lowered Due to Setbacks in Clinical Trials but Pipeline Development Continues

As we have highlighted, Takeda continues to make good progress with its development pipeline where the company has received FDA approval for...

Shifara Samsudeen, ACMA, CGMA

Takeda: Earnings Beat Driven by Key Drugs and Dengue Vaccine Seeing Positive Momentum

Takeda's 1QFY24 earnings beat consensus driven by growth & launch products. Newly launched dengue vaccine has started generating revenues with new...

Shifara Samsudeen, ACMA, CGMA

Takeda Pharmaceuticals: Does It Have A Sustainable Competitive Advantage? – Key Drivers

Takeda delivered a mixed set of results for the previous quarter, with revenues below the analyst consensus. Takeda also achieved strong financial...

Baptista Research

Cooperation with Takeda saves Ascentage from survival problem, but self-building sales team remains a challenge. Investors eye anther deal with...