External broker reports(aggregated public sources), CMB International

CMB International

Incorporated in Hong Kong, supported by the mainland and targeting in global market, CMB International Capital Corporation Limited (“CMBI”) is an integrated financial institution providing comprehensive and professional services. As a wholly-owned subsidiary of China Merchants Bank ("CMB"), by leveraging on the Group’s synergy and coordination in domestic and overseas markets, as well as CMB’s strong resources and outstanding social reputation, CMBI and its subsidiaries have been actively implementing diversified business strategies and set up an overall layout of main business segments including Corporate Finance, Asset Management, Wealth Management, Global Markets and Structured Finance, etc. Adhering to the philosophy of “being clients oriented and increasing our own values by the way of creating value for clients”, CMBI endeavors to provide quality and integrated financial services to institutional, corporate and individual customers both domestic and overseas including Hong Kong IPO sponsorship and underwriting, share placement and rights issue for listed companies, financial advisors, bonds issuance services, asset management, direct investment, wealth management, equity sales and trading, etc.

External broker reports(aggregated public sources)

Equity Bottom-Up

Jacobio Pharmaceuticals / Equity Bottom-Up

<ul><li>Jacobio’s JAB-23E73 (pan-KRAS) has demonstrated a highly differentiated safety profile and promising early efficacy.</li><li>We believe that due to its superior safety compared to competitors like RVMD’s RMC-6236 and encouraging early efficacy signals, JAB-23E73 holds significant blockbuster potential.</li><li>We estimate the global risk-adjusted peak sales of JAB-23E73 to reach US$2.1bn. </li></ul><p><em>Content is external broker report sourced from online content aggregator through publicly available sources and is displayed below for general informational purposes only. Refer full disclaimer below.</em></p>

Jacobio’s JAB-23E73 (pan-KRAS) has demonstrated a highly differentiated safety profile and promising early efficacy.We believe that due to its superior safety compared to competitors like RVMD’s RMC-6236 and encouraging early efficacy signals, JAB-23E73 holds significant blockbuster potential.We estimate the global risk-adjusted peak sales of JAB-23E73 to reach US$2.1bn. Content is external broker report sourced from online content aggregator through publicly available sources and is displayed below for general informational purposes only. Refer full disclaimer below.

Jacobio (1167 HK) - Early Pan-KRAS Clinical Data Unveils Potential First-In-Class Blockbuster