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Protalix BioTherapeutics  / Equity Bottom-Up

<ul><li>Protalix is a clinical and commercial pharmaceutical company using its proprietary ProCellEx plant-based expression system to pro duce thera peutic proteins for global markets.</li><li>The company has two commer cialized products, Elelyso that is marketed by Fiocruz in Brazil & Pfizer in the rest of the world for Gaucher Disease and Elfabrio which was approved in May 2023.</li><li>Chiesi Rare Disease will commercialize Elfabrio globally.</li></ul>

Protalix is a clinical and commercial pharmaceutical company using its proprietary ProCellEx plant-based expression system to pro duce thera peutic proteins for global markets.The company has two commer cialized products, Elelyso that is marketed by Fiocruz in Brazil & Pfizer in the rest of the world for Gaucher Disease and Elfabrio which was approved in May 2023.Chiesi Rare Disease will commercialize Elfabrio globally.

Protalix BioTherapeutics

PLX: Chiesi Milestone Received