Macro Strategist, Saxo Capital Markets

Kay Van-Petersen

Macro Strategist

Saxo Capital Markets

Thematic (Sector/Industry)

<ul><li>Post SNB surprise announcement yesterday - after leading the market on as recently as a few weeks ago on – the term “Never trust a Swiss central banker” will soon become mainstream.&nbsp; </li><li>In this piece, KVP takes a snap shot of what happened, the significance &amp; potential ways to look to play things going forward. </li></ul>

Post SNB surprise announcement yesterday - after leading the market on as recently as a few weeks ago on – the term “Never trust a Swiss central banker” will soon become mainstream.&nbsp; In this piece, KVP takes a snap shot of what happened, the significance &amp; potential ways to look to play things going forward. 

Global Healthcare Analyst

Tina Banerjee

Equity Bottom-Up

<ul>
<li>
<a href="https://www.smartkarma.com/entities/remegen-co-ltd" target="_blank" data-smartkarma-citation="entities:29191:1" rel="noopener">Remegen (9995 HK)</a> entered an exclusive outlicensing agreement with <a href="https://www.smartkarma.com/entities/abbvie-inc" target="_blank" data-smartkarma-citation="entities:1135:1" rel="noopener">Abbvie Inc (ABBV US)</a>  regarding RC148, a novel investigational PD-1/ VEGF bispecific antibody drug candidate for an upfront payment of $650M.</li>
<li>Remegen is eligible to receive up to $4.95B in development, regulatory, and commercial milestone payments, as well as tiered double-digit royalty payments on net sales outside the Greater China region.</li>
<li>RC148 is currently being developed in China by Remegen as a monotherapy and in combination for treating patients with various advanced malignant solid tumors, including certain lung cancers.</li>
</ul>



Remegen (9995 HK) entered an exclusive outlicensing agreement with Abbvie Inc (ABBV US)  regarding RC148, a novel investigational PD-1/ VEGF bispecific antibody drug candidate for an upfront payment of $650M.
Remegen is eligible to receive up to $4.95B in development, regulatory, and commercial milestone payments, as well as tiered double-digit royalty payments on net sales outside the Greater China region.
RC148 is currently being developed in China by Remegen as a monotherapy and in combination for treating patients with various advanced malignant solid tumors, including certain lung cancers.


Remegen (9995 HK): New Licensing Deal With AbbVie Brings $650M Upfront Cash

Independent research on the U.S. markets, Baptista Research

Baptista Research

Independent research on the U.S. markets

Baptista Research is an independent financial research house focused on the U.S. markets. We provide equity research as well as credit research reports on the top-listed U.S. companies with most of our focus on technology, consumer goods and services, automobiles, industrials, oil and gas, pharma, and healthcare. Our research has served more than 3000 institutional investors including mutual funds, hedge funds, banks, family offices, and various buy-side firms. We operate a research subscription service where institutions, as well as retail investors, can have priority access to all our research. We also have a wide distribution of our research reports across some of the top global financial platforms. Apart from equity research and credit research, we also provide advisory services with respect to mergers & acquisitions (M&A), private equity/ venture capital fundraising, valuation reports, and investment management services for corporates.
Baptista Research is owned and managed by Ishan Majumdar, an ex-Venture Capitalist/ Investment Banker, a Chartered Accountant, and a Masters’ degree holder in Management from HEC Paris. Ishan has nearly a decade of experience in Mergers and Acquisitions, Leveraged Buyouts (LBOs), Venture Capital Investing, Corporate Strategy, and Valuation in front-office roles at the likes of BNP Paribas CIB, Credit Agricole CIB, Groupe Danone, and TIW Private Equity. He has worked on and closed multiple acquisition deals, leveraged buyouts, and start-up investment transactions.

Bristol Myers Squibb Co / Equity Bottom-Up

<ul><li>Bristol Myers Squibb has made headlines once again—this time with its $1.5 billion all-cash agreement to acquire Orbital Therapeutics, a privately held biotechnology company pioneering nextgeneration RNA therapies.</li><li>The deal represents a significant move by Bristol to bolster its innovation pipeline amid looming patent expirations, increased payer scrutiny, and a shifting regulatory landscape.</li><li>Orbital Therapeutics' platform, which integrates circular and linear RNA engineering with AI-driven design and advanced lipid nanoparticle delivery, is anchored by its lead candidate OTX-201—an RNA immunotherapy targeting autoimmune disease via B cell depletion.</li></ul>

Bristol Myers Squibb has made headlines once again—this time with its $1.5 billion all-cash agreement to acquire Orbital Therapeutics, a privately held biotechnology company pioneering nextgeneration RNA therapies.The deal represents a significant move by Bristol to bolster its innovation pipeline amid looming patent expirations, increased payer scrutiny, and a shifting regulatory landscape.Orbital Therapeutics' platform, which integrates circular and linear RNA engineering with AI-driven design and advanced lipid nanoparticle delivery, is anchored by its lead candidate OTX-201—an RNA immunotherapy targeting autoimmune disease via B cell depletion.

Bristol Myers' $1.5 Billion RNA Gamble: Could Orbital Therapeutics Rewire Its Future?

Smartkarma AI Primers, Smartkarma

αSK Primers

Smartkarma AI Primers

Smartkarma

Smartkarma unites the fragmented investment industry, connecting institutional investors, independent research providers, and corporates within a single network.

Research Reinvented

<ul>
 <li>
<a href="https://smartkarma.com/entities/bristol-myers-squibb-co-eb9aefc7-c84b-492b-ad35-ff0f93d31d45">Bristol-Myers Squibb </a>is a global biopharmaceutical company facing a significant patent cliff for key revenue drivers like Eliquis and Opdivo, creating near-term revenue headwinds.</li>
 <li>The company's strategy to mitigate these losses centers on its growing portfolio of new products, a robust R&amp;D pipeline focused on oncology, immunology, and cardiovascular diseases, and strategic acquisitions to replenish its drug pipeline.</li>
 <li>While navigating a challenging period of patent expirations and increasing competition, the company's strong cash flow, commitment to its dividend, and investments in innovative platforms like cell therapy and radiopharmaceuticals present a long-term growth thesis.</li>
</ul>This content is AI-generated and displayed for general informational purposes only. Please verify independently before use.


  
Bristol-Myers Squibb is a global biopharmaceutical company facing a significant patent cliff for key revenue drivers like Eliquis and Opdivo, creating near-term revenue headwinds.
  The company's strategy to mitigate these losses centers on its growing portfolio of new products, a robust R&amp;D pipeline focused on oncology, immunology, and cardiovascular diseases, and strategic acquisitions to replenish its drug pipeline.
  While navigating a challenging period of patent expirations and increasing competition, the company's strong cash flow, commitment to its dividend, and investments in innovative platforms like cell therapy and radiopharmaceuticals present a long-term growth thesis.
This content is AI-generated and displayed for general informational purposes only. Please verify independently before use.

Primer: Bristol-Myers Squibb  (BMY UN) - Sep 2025

Equity Capital Markets

Genfleet Therapeutics / Equity Capital Markets

<ul>
<li>Genfleet Therapeutics has filed for IPO to raise up to HK$1.6B. The company plans to sell 77.6M shares at HK$20.39 per share.</li>
<li>Genfleet Therapeutics is a biopharmaceutical company focused on developing novel treatment options in the fields of oncology with its core products focused on niche RAS inhibitor segment.</li>
<li>Genfleet is rightly placed to rapidly advance their innovative product pipeline to later stages of development and commercialize. Pipeline envisages sustainable long term growth prospect.</li>
</ul>


Genfleet Therapeutics has filed for IPO to raise up to HK$1.6B. The company plans to sell 77.6M shares at HK$20.39 per share.
Genfleet Therapeutics is a biopharmaceutical company focused on developing novel treatment options in the fields of oncology with its core products focused on niche RAS inhibitor segment.
Genfleet is rightly placed to rapidly advance their innovative product pipeline to later stages of development and commercialize. Pipeline envisages sustainable long term growth prospect.


Genfleet Therapeutics IPO: Finely Placed at the Moment; RAS Inhibitors Hold Key to Future Growth

United States

Bristol-Myers Squibb Company is a global biopharmaceutical company. The Company develops, licenses, manufactures, markets, and sells pharmaceutical and nutritional products. Bristol-Myers Squibb products and experimental therapies address cancer, heart disease, HIV/AIDS, diabetes, rheumatoid arthritis, hepatitis, organ transplant  rejection, and psychiatric disorders.

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Bristol Myers Squibb Co (BMY US)

Never Trust A Swiss Central Banker

Post SNB surprise announcement yesterday - after leading the market on as recently as a few weeks ago on – the term “Never trust a Swiss central...

Kay Van-Petersen

Remegen (9995 HK): New Licensing Deal With AbbVie Brings $650M Upfront Cash

Remegen inked an exclusive outlicensing deal with AbbVie for RC148, an investigational PD-1/ VEGF bispecific antibody drug candidate for an upfront...

Tina Banerjee

Bristol Myers' $1.5 Billion RNA Gamble: Could Orbital Therapeutics Rewire Its Future?

Bristol Myers Squibb has made headlines once again—this time with its $1.5 billion all-cash agreement to acquire Orbital Therapeutics, a privately...

Baptista Research

Primer: Bristol-Myers Squibb (BMY UN) - Sep 2025

Bristol-Myers Squibb is a global biopharmaceutical company facing a significant patent cliff for key revenue drivers like Eliquis and Opdivo,...

αSK Primers

Genfleet Therapeutics IPO: Finely Placed at the Moment; RAS Inhibitors Hold Key to Future Growth

Genfleet Therapeutics has filed for HK IPO to raise up to HK$1.6B. The company plans to sell 77.6M shares at HK$20.39 per share. The IPO will close...

Tina Banerjee

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