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External broker reports(aggregated public sources)

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Equity Bottom-Up

Clarity Pharmaceuticals Ltd / Equity Bottom-Up

<ul><li>Clarity have announced additional data from their Phase I/IIa SECuRE trial in metastatic castrate resistant prostate cancer (mCRPC).</li><li>Cohort 3 has dosed the first 3 patients with the highest 12GBq dose of 67Cu-SAR-bisPSMA, and the data safety review board have green lighted recruitment of the final 3 patients for this cohort after a lack of observation in dose limiting toxicities (DLTs).</li><li>This is a huge win for Clarity with safety and tolerability the initial focus of this dose escalation phase of the SECuRE trial. </li></ul><p><em>Content is external broker report sourced from online content aggregator through publicly available sources and is displayed below for general informational purposes only. Refer full disclaimer below.</em></p>

Clarity have announced additional data from their Phase I/IIa SECuRE trial in metastatic castrate resistant prostate cancer (mCRPC).Cohort 3 has dosed the first 3 patients with the highest 12GBq dose of 67Cu-SAR-bisPSMA, and the data safety review board have green lighted recruitment of the final 3 patients for this cohort after a lack of observation in dose limiting toxicities (DLTs).This is a huge win for Clarity with safety and tolerability the initial focus of this dose escalation phase of the SECuRE trial. Content is external broker report sourced from online content aggregator through publicly available sources and is displayed below for general informational purposes only. Refer full disclaimer below.

Clarity Pharmaceuticals (CU6) - Copper Firing: PSMA Tx and Dx Updates

<div><div><div><ul><li>We maintain our OVERWEIGHT rating on Clarity Pharmaceuticals and increase our risked PT to $1.55/sh (unrisked $5.19/sh).</li><li>The key takeaway from Clarity over the last year is that the company are pushing well ahead of expected timelines to equip themselves with two prostate cancer (PC) diagnostic products in the market by FY26e - 64Cu-SAR-bisPSMA for PSMA avid PC, soon followed by 64Cu-SAR-Bombesin for non-PSMA avid PC.</li><li>Clarity’s efforts have been impressive, as has their early data in their PSMA avid diagnostic and therapy trials, showing potential practice-changing benefits over current radiopharmaceutical offerings. </li></ul></div></div></div><p><em>Content is external broker report sourced from online content aggregator through publicly available sources and is displayed below for general informational purposes only. Refer full disclaimer below.</em></p>

We maintain our OVERWEIGHT rating on Clarity Pharmaceuticals and increase our risked PT to $1.55/sh (unrisked $5.19/sh).The key takeaway from Clarity over the last year is that the company are pushing well ahead of expected timelines to equip themselves with two prostate cancer (PC) diagnostic products in the market by FY26e - 64Cu-SAR-bisPSMA for PSMA avid PC, soon followed by 64Cu-SAR-Bombesin for non-PSMA avid PC.Clarity’s efforts have been impressive, as has their early data in their PSMA avid diagnostic and therapy trials, showing potential practice-changing benefits over current radiopharmaceutical offerings. Content is external broker report sourced from online content aggregator through publicly available sources and is displayed below for general informational purposes only. Refer full disclaimer below.

Clarity Pharmaceuticals (CU6) - No Prostates Left Behind

<div><div><div><ul><li>Clarity Pharmaceuticals’ Phase I/IIa SECuRE trial evaluating their 64Cu/67Cu-SAR-bisPSMA theranostic pair in metastatic castrate-resistant prostate cancer (mCRPC) has completed Cohort 2 and progresses to Cohort 3 enrolment.</li><li>Importantly, the responses of the three patients treated in Cohort 2 with a single 8GBq dose of CU6’s PSMA therapeutic asset (67Cu-SAR-bisPSMA) have shown material reductions in PSA levels (a key surrogate efficacy endpoint).</li><li>Two of the three patients experienced ~90% PSA reductions, which is an impressive response considering this is following just one 8GBq dose. </li></ul></div></div></div><p><em>Content is external broker report sourced from online content aggregator through publicly available sources and is displayed below for general informational purposes only. Refer full disclaimer below.</em></p>

Clarity Pharmaceuticals’ Phase I/IIa SECuRE trial evaluating their 64Cu/67Cu-SAR-bisPSMA theranostic pair in metastatic castrate-resistant prostate cancer (mCRPC) has completed Cohort 2 and progresses to Cohort 3 enrolment.Importantly, the responses of the three patients treated in Cohort 2 with a single 8GBq dose of CU6’s PSMA therapeutic asset (67Cu-SAR-bisPSMA) have shown material reductions in PSA levels (a key surrogate efficacy endpoint).Two of the three patients experienced ~90% PSA reductions, which is an impressive response considering this is following just one 8GBq dose. Content is external broker report sourced from online content aggregator through publicly available sources and is displayed below for general informational purposes only. Refer full disclaimer below.

Clarity Pharmaceuticals (CU6)M - SECuRE Cohort 2 Data Impresses

<div><div><div><ul><li>We maintain our OVERWEIGHT rating on Clarity Pharmaceuticals and risked price target of $1.22/sh.</li><li>The company’s 67Cu manufacturing partner (NorthStar Medical Isotopes; NSMI) held a site tour last week in Wisconsin.</li><li>We attended to validate progress and to discuss matters of purification, yield, supply chain and regulatory pathways. </li></ul></div></div></div><p><em>Content is external broker report sourced from online content aggregator through publicly available sources and is displayed below for general informational purposes only. Refer full disclaimer below.</em></p>

We maintain our OVERWEIGHT rating on Clarity Pharmaceuticals and risked price target of $1.22/sh.The company’s 67Cu manufacturing partner (NorthStar Medical Isotopes; NSMI) held a site tour last week in Wisconsin.We attended to validate progress and to discuss matters of purification, yield, supply chain and regulatory pathways. Content is external broker report sourced from online content aggregator through publicly available sources and is displayed below for general informational purposes only. Refer full disclaimer below.

Clarity Pharmaceuticals (CU6) - BEAM ON in Wisconsin

<div><div><div><ul><li>Clarity have announced that their exclusive manufacturing partner, NorthStar Radioisotopes, have successfully completed large scale manufacturing runs of their therapeutic radioisotope, 67- Copper, for use in Clarity’s ongoing clinical trial programs (SeCURE, COMBAT, CL04).</li><li>This is a huge milestone for Clarity and NorthStar with large scale production of this isotope being the key impediment to its development as a therapeutic isotope in years past.</li><li>Novel methods utilizing electron accelerator technology have enabled high purity, large scale 67-Cu isolation, which is critical to enable Clarity’s pipeline development across their prostate (PSMA-avid SeCURE; non- PSMA avid COMBAT) and Neuroblastoma (CL04) programs. </li></ul></div></div></div><p><em>Content is external broker report sourced from online content aggregator through publicly available sources and is displayed below for general informational purposes only. Refer full disclaimer below.</em></p>

Clarity have announced that their exclusive manufacturing partner, NorthStar Radioisotopes, have successfully completed large scale manufacturing runs of their therapeutic radioisotope, 67- Copper, for use in Clarity’s ongoing clinical trial programs (SeCURE, COMBAT, CL04).This is a huge milestone for Clarity and NorthStar with large scale production of this isotope being the key impediment to its development as a therapeutic isotope in years past.Novel methods utilizing electron accelerator technology have enabled high purity, large scale 67-Cu isolation, which is critical to enable Clarity’s pipeline development across their prostate (PSMA-avid SeCURE; non- PSMA avid COMBAT) and Neuroblastoma (CL04) programs. Content is external broker report sourced from online content aggregator through publicly available sources and is displayed below for general informational purposes only. Refer full disclaimer below.

Clarity Pharmaceuticals (CU6) - 67 Cu Is a Go!

Australia

Clarity Pharmaceuticals Limited operates as a radio-pharmaceutical company. The Company focuses on the developing targeted therapies for the treatment of cancer and other serious diseases. Clarity Pharmaceuticals serves customers worldwide.

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Clarity Pharmaceuticals Ltd (CU6 AU)

Clarity Pharmaceuticals (CU6) - Copper Firing: PSMA Tx and Dx Updates

Clarity have announced additional data from their Phase I/IIa SECuRE trial in metastatic castrate resistant prostate cancer (mCRPC).

Wilsons Advisory

Clarity Pharmaceuticals (CU6) - No Prostates Left Behind

We maintain our OVERWEIGHT rating on Clarity Pharmaceuticals and increase our risked PT to $1.55/sh (unrisked $5.19/sh).

Wilsons Advisory

Clarity Pharmaceuticals (CU6)M - SECuRE Cohort 2 Data Impresses

Two of the three patients experienced ~90% PSA reductions, which is an impressive response considering this is following just one 8GBq dose.

Wilsons Advisory

Clarity Pharmaceuticals (CU6) - BEAM ON in Wisconsin

The company’s 67Cu manufacturing partner (NorthStar Medical Isotopes; NSMI) held a site tour last week in Wisconsin. We attended to validate...

Wilsons Advisory

Clarity Pharmaceuticals (CU6) - 67 Cu Is a Go!

This is a huge milestone for Clarity and NorthStar with large scale production of this isotope being the key impediment to its development as a...

Wilsons Advisory

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