Independent research on the U.S. markets, Baptista Research

Baptista Research

Independent research on the U.S. markets

Baptista Research is an independent financial research house focused on the U.S. markets. We provide equity research as well as credit research reports on the top-listed U.S. companies with most of our focus on technology, consumer goods and services, automobiles, industrials, oil and gas, pharma, and healthcare. Our research has served more than 3000 institutional investors including mutual funds, hedge funds, banks, family offices, and various buy-side firms. We operate a research subscription service where institutions, as well as retail investors, can have priority access to all our research. We also have a wide distribution of our research reports across some of the top global financial platforms. Apart from equity research and credit research, we also provide advisory services with respect to mergers & acquisitions (M&A), private equity/ venture capital fundraising, valuation reports, and investment management services for corporates.
Baptista Research is owned and managed by Ishan Majumdar, an ex-Venture Capitalist/ Investment Banker, a Chartered Accountant, and a Masters’ degree holder in Management from HEC Paris. Ishan has nearly a decade of experience in Mergers and Acquisitions, Leveraged Buyouts (LBOs), Venture Capital Investing, Corporate Strategy, and Valuation in front-office roles at the likes of BNP Paribas CIB, Credit Agricole CIB, Groupe Danone, and TIW Private Equity. He has worked on and closed multiple acquisition deals, leveraged buyouts, and start-up investment transactions.

Equity Bottom-Up

Intellia Therapeutics  / Equity Bottom-Up

<ul><li>Intellia Therapeutics shares nosedived by 40% on October 27, 2025, after the company abruptly paused two critical Phase 3 clinical trials for its lead gene-editing candidate, nex-z.</li><li>The suspension follows the hospitalization of an elderly patient treated with nex-z who experienced elevated liver enzymes and bilirubin levels—early markers of liver injury.</li><li>This development casts a dark cloud over nex-z, a therapy that had been projected to drive 62% of Intellia’s estimated 2030 revenues and was central to the company’s valuation narrative.</li></ul>

Intellia Therapeutics shares nosedived by 40% on October 27, 2025, after the company abruptly paused two critical Phase 3 clinical trials for its lead gene-editing candidate, nex-z.The suspension follows the hospitalization of an elderly patient treated with nex-z who experienced elevated liver enzymes and bilirubin levels—early markers of liver injury.This development casts a dark cloud over nex-z, a therapy that had been projected to drive 62% of Intellia’s estimated 2030 revenues and was central to the company’s valuation narrative.

Intellia Therapeutics Stock Plunge: What Does The Safety Scare In Gene-Editing Trials Mean?

Technical Analyst, Vermilion Research

Joe Jasper

Technical Analyst

Technical and Quantitative Research

Vermilion Research

Vermilion’s objective is to deliver timely, actionable, and unique technical research to professional investors through the application of our various technical indicators.

Our research strategists seek to highlight securities which we believe are at major inflection points, based on our various technical and quantitative indicators, and offer asymmetric risk/return profiles. Our unique research methodology, centered on relative strength, enables our strategists to deliver superior investment recommendations.

Our process begins by organizing the universe of actively traded stocks into discrete sectors, then into industry groups. We then apply our technical and quantitative tools to identify developing price trends. Once attractive trends are identified within a selected sector or group, we screen for individual stocks which we believe offer the best risk/reward profile. We provide a historical perspective that often reveals, through our long-term charts, how price patterns often repeat themselves over time.

Technical Analysis

<ul>
<li>We remain bullish since our 4/22/25 Compass, and we will maintain our bullish outlook as long as market dynamics remain healthy and the S&amp;P 500 (SPX) is above 6028-6059.</li>
<li>For now, we continue to expect support to show up at the 4-month uptrend, which generally coincides with the 20-day MA.</li>
<li>Speculative growth themes and metals/mining (GDX, XME) remain leadership, which we expect to continue through year-end and into the early part of 2026</li>
</ul>


We remain bullish since our 4/22/25 Compass, and we will maintain our bullish outlook as long as market dynamics remain healthy and the S&amp;P 500 (SPX) is above 6028-6059.
For now, we continue to expect support to show up at the 4-month uptrend, which generally coincides with the 20-day MA.
Speculative growth themes and metals/mining (GDX, XME) remain leadership, which we expect to continue through year-end and into the early part of 2026


S&P 500 and Russell 2000 4+ Month Uptrends Intact; Stick With Growth Themes and Metals/Mining

Fundamental Short Selling Research

Eric Fernandez, CFA

TwoRiversAnalytics

MSC Industrial Direct Co Inc / Equity Bottom-Up

Liquidity shorts can be great short candidates.  These shorts tend to have moderate to higher betas, time horizons of six to twelve months, and can have strong down moves as the liquidity crisis gets closer in time.  They can also go bankrupt, pushing the stock price close to zero.  See formatted report attached, and content pasted below.

Liquidity shorts can be great short candidates.  These shorts tend to have moderate to higher betas, time horizons of six to twelve months, and can have strong down moves as the liquidity crisis gets closer in time.  They can also go bankrupt, pushing the stock price close to zero.  See formatted report attached, and content pasted below.

Liquidity Risk Short Candidates: MSC Indus, Alphatec, Intellia Thera, PAR Tech

Latest News from the World’s Leading Innovators

Granite Bay Capital

An innovation focussed investment company

Granite Bay Capital is an innovation focussed investment company with a deep focus on the companies at the leading edge of innovation across major themes such as AI, ubiquitous computing, sustainability, automation and longevity.

Thematic (Sector/Industry)

Headline Developments: We can now modify DNA inside of a human body (in vivo), thanks to some groundbreaking work announced this week by Intellia Therapeutics (NTLA) which saw the company’s share price surge 55%.  What this means is that we can now send precision therapeutics (based on CRISPR technology) to “seek and destroy” problematic genes.

Headline Developments: We can now modify DNA inside of a human body (in vivo), thanks to some groundbreaking work announced this week by Intellia Therapeutics (NTLA) which saw the company’s share price surge 55%.  What this means is that we can now send precision therapeutics (based on CRISPR technology) to “seek and destroy” problematic genes.

We continue to see signs of improving risk appetites alongside healthy market dynamics. As a result, our outlook remains constructive. A breakout to new highs in the Russell 2000 (IWM) and Russell Micro-Caps (IWC), above $234.50 and $159, would likely cause us to shift to an outright bullish stance. In today’s report we highlight attractive Groups and stocks within Consumer Discretionary, Technology, and Health Care.

We continue to see signs of improving risk appetites alongside healthy market dynamics. As a result, our outlook remains constructive. A breakout to new highs in the Russell 2000 (IWM) and Russell Micro-Caps (IWC), above $234.50 and $159, would likely cause us to shift to an outright bullish stance. In today’s report we highlight attractive Groups and stocks within Consumer Discretionary, Technology, and Health Care.

U.S. Yields Testing Support Ahead Of FOMC Meeting

United States

Intellia Therapeutics, Inc. operates as a biotechnology company. The Company focuses on the research and clinical development of gene editing therapies for patients with genetically-based diseases.

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Intellia Therapeutics (NTLA US)

Intellia Therapeutics Stock Plunge: What Does The Safety Scare In Gene-Editing Trials Mean?

Intellia Therapeutics shares nosedived by 40% on October 27, 2025, after the company abruptly paused two critical Phase 3 clinical trials for its...

Baptista Research

S&P 500 and Russell 2000 4+ Month Uptrends Intact; Stick With Growth Themes and Metals/Mining

S&P 500 and Russell 2000 4+ Month Uptrends Intact; Stick With Growth Themes and Metals/Mining $GDX $XME $ARKG $ARKK $ARKQ $ARKX $ARKW $ARKF $GRAL...

Vermilion Research

Liquidity Risk Short Candidates: MSC Indus, Alphatec, Intellia Thera, PAR Tech

Liquidity Risk Short Candidates: MSC Indus, Alphatec, Intellia Thera, PAR Tech. All show tight cash positions, some show significant cash burn and...

Eric Fernandez, CFA

Weekly Innovation Review (WIRE) #38

Headline Developments: We can now modify DNA inside of a human body (in vivo), thanks to some groundbreaking work announced this week

Granite Bay Capital

U.S. Yields Testing Support Ahead Of FOMC Meeting

We continue to see signs of improving risk appetites alongside healthy market dynamics. As a result, our outlook remains constructive.

Vermilion Research

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