Daily BriefsHealthcare

Daily Brief Health Care: Blue Jet Healthcare Ltd, Metsera, Sigachi Industries , 23andMe Holding Co, Maze Therapeutics, Olba Healthcare Holdings, Stryker Corp, Chugai Pharmaceutical, Jcr Pharmaceuticals, Lexicon Pharmaceuticals and more

In today’s briefing:

  • The Beat Ideas: Blue Jet Healthcare- Rising CDMO Player
  • Metsera Inc (MTSR): GLP-1 Boom Comes to the IPO Market with Explosive Debut
  • The Beat Ideas: Sigachi Industries- High Growth, Revenue Diversification, New Category Launch
  • 23andMe On The Brink? Exploring a Potential Sale Amid Financial Struggles!
  • Maze Therapeutics (MAZE): Upsized IPO Slumps in the Aftermarket
  • Olba Healthcare Holdings (2689 JP): 1H FY06/25 flash update
  • Stryker Corporation: Leveraging Mako Robotic-Assisted Surgeries To Redefine the Industry! – Major Drivers
  • Chugai Pharmaceutical (4519 JP): Export Drives 2024 Result; Slower Growth Expected In 2025
  • JCR Pharmaceutical (4552 JP): Sluggish 9MFY25 Performance, Guidance Revised Downward
  • Lexicon’s FDA Rejection, Layoffs, and Nasdaq Delisting Threat: Can It Get Acquired?


The Beat Ideas: Blue Jet Healthcare- Rising CDMO Player

By Sudarshan Bhandari

  • Blue Jet Healthcare Ltd (BJHC IN) is a science-led pharmaceutical company that has evolved into a strategic partner for the CDMO of advanced Pharmaceutical Intermediates and APIs.
  • Company gave a record breaking Q3FY25 primarily driven by capacity expansion in Contrast media and PI Segment. Strong demand for the cardiovascular product was also witnessed.
  • Company commissioned an additional manufacturing block during Q3 FY25 at Ambernath for manufacturing Advance Contrast Media with investment around Rs. 100Mn.

Metsera Inc (MTSR): GLP-1 Boom Comes to the IPO Market with Explosive Debut

By IPO Boutique

  • Metsera (MTSR US), a biotech using peptides to treat obesity, overweight and related conditions opened 41.7% above the issue price. 
  • The company was seeking a specific cash-raise of $275 million and was not looking to allow further dilution.
  • IPOs in the biotech sector are a “sell-the-news” event until we see on the tape otherwise.

The Beat Ideas: Sigachi Industries- High Growth, Revenue Diversification, New Category Launch

By Sudarshan Bhandari

  • Sigachi Industries (SIGACHI IN)  has increased MCC capacity to 21,700 MTPA and expects to achieve 80-90% utilization by Q4 FY27 from 50% utilization in Q4FY25.
  • Sigachi is increasing its focus on the API segment, with a target of 20-25% revenue contribution in next 2-3 yrs and further expanding to 35-40% of revenue in 3-5 Yrs.
  • Sigachi is introducing new product lines including pharmaceutical coatings like PureCoat and UltraMod and plans to commercialize Croscarmellose Sodium (CCS) by FY26 to enhance drug stability and bioavailability.

23andMe On The Brink? Exploring a Potential Sale Amid Financial Struggles!

By Baptista Research

  • 23andMe’s recent earnings report reveals a period of significant transition and strategic refocus for the company, characterized by financial adjustments, business restructuring, and an evolving operational strategy.
  • These developments present a nuanced view of the company’s current state and future potential in the health genetics and consumer genomics sector.
  • On the positive side, 23andMe reported strides in its overarching goal to achieve cash-flow positivity.

Maze Therapeutics (MAZE): Upsized IPO Slumps in the Aftermarket

By IPO Boutique

  • Maze Therapeutics (MAZE US) upsized its transaction but saw its IPO price dip below issue on day one.
  • A critical piece of information, price guidance, was missing from the final channel check sending a warning message to the market.
  • With the lack of enthusiasm for this IPO during its first session, we would encourage investors to exercise caution on this IPO in the aftermarket.

Olba Healthcare Holdings (2689 JP): 1H FY06/25 flash update

By Shared Research

  • The company’s sales and profits are concentrated in Q3 due to medical equipment deliveries to public institutions.
  • Medical Devices and Consumables segment sales rose 7.6% YoY, driven by consumables and strategic regional sales activities.
  • SPD business sales increased 9.8% YoY, with operating profit up 5.3% YoY, despite rising SG&A expenses.

Stryker Corporation: Leveraging Mako Robotic-Assisted Surgeries To Redefine the Industry! – Major Drivers

By Baptista Research

  • Stryker Corporation reported strong financial performance in its fourth quarter of 2024 and the full fiscal year, demonstrating resilience and robust growth across its business segments.
  • The company’s organic sales growth exceeded 10% for both periods, with U.S. sales growth at 10.6% and international sales at 8.8%.
  • Key drivers included double-digit growth in the Instruments, Endoscopy, Medical, Neuro Cranial, and Trauma and Extremities businesses.

Chugai Pharmaceutical (4519 JP): Export Drives 2024 Result; Slower Growth Expected In 2025

By Tina Banerjee

  • Chugai Pharmaceutical (4519 JP) announced stellar performance in 2024, with revenue, operating profit, and net income exceeded revised forecasts, all reaching record highs.
  • Export of Hemlibra to Roche increased 45% YoY to ¥304B. Roche is seeing strong uptake of Hemlibra in Europe, where the drug reported double-digit growth.
  • Chugai guided for 2% revenue growth in 2025. Domestic sales are expected to remain flat, while overseas sales are expected to increase 4%. Bottomline to outpace revenue growth.

JCR Pharmaceutical (4552 JP): Sluggish 9MFY25 Performance, Guidance Revised Downward

By Tina Banerjee

  • Jcr Pharmaceuticals (4552 JP) revenue dropped 23% to ¥26B during 9MFY25, dragged by lower contractual payments. With higher R&D and SG&A expenses, the company reported operating loss of ¥754M.
  • FY25 Guidance has been revised downwards with revised sales now stands at ¥39B. While product sales remain largely on track, income from contractual payment was revised downward.
  • The heavy dependence on one major product and no major product launch lined up anytime soon poses as a negative on the company’s prospects in near future.

Lexicon’s FDA Rejection, Layoffs, and Nasdaq Delisting Threat: Can It Get Acquired?

By Baptista Research

  • Lexicon Pharmaceuticals, a biopharmaceutical company focused on developing treatments for serious diseases, recently shared their third-quarter 2024 financial results and provided business updates.
  • Among their key areas of activity are their drug programs including INPEFA, ZYNQUISTA, LX9211, and LX9851.
  • This quarter marked significant developments for Lexicon as they continued their strategic initiatives and focused on advancing their pipeline.

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