Daily BriefsHealthcare

Daily Brief Health Care: China Medical System, GenFleet Therapeutics, Cybin , LB Pharmaceuticals and more

In today’s briefing:

  • China Medical System (867 HK) – From an 8 to a 16 FPE
  • Genfleet Therapeutics IPO: Finely Placed at the Moment; RAS Inhibitors Hold Key to Future Growth
  • Cybin, Inc: CYB004 Completes Enrollment; Top-Line Read Expected in 1Q26
  • LB Pharmaceuticals Inc. (LBRX): Strong Open, Schizophrenia Biotech Finds Early Momentum


China Medical System (867 HK) – From an 8 to a 16 FPE

By Avien Pillay

  • Since our initiation on 5 June 2024, China Medical Sytem’s share price is up 113% and the FPE has moved from less than 8 to close to 16 times.
  • The gap valuation between US drug companies and CMS has largely closed with CMS trading at a premium to a number of US counterparts.
  • The earnings outlook is largely flat since the initiation, implying the share price appreciation has been driven by a re-rating.

Genfleet Therapeutics IPO: Finely Placed at the Moment; RAS Inhibitors Hold Key to Future Growth

By Tina Banerjee

  • Genfleet Therapeutics has filed for IPO to raise up to HK$1.6B. The company plans to sell 77.6M shares at HK$20.39 per share.
  • Genfleet Therapeutics is a biopharmaceutical company focused on developing novel treatment options in the fields of oncology with its core products focused on niche RAS inhibitor segment.
  • Genfleet is rightly placed to rapidly advance their innovative product pipeline to later stages of development and commercialize. Pipeline envisages sustainable long term growth prospect.

Cybin, Inc: CYB004 Completes Enrollment; Top-Line Read Expected in 1Q26

By Water Tower Research

  • CYB004 completes patient enrollment to push Phase 2 study toward the finish line.
  • Cybin has confirmed that it has enrolled its 36th and final patient for its Phase 2 CYB004 program to evaluate the safety and efficacy of its proprietary short-acting deuterated version of DMT for the treatment of generalized anxiety disorder (GAD) at six and 12 weeks after first dose.
  • Top-line data of the Phase 2 study is expected to be forthcoming in 1Q26.

LB Pharmaceuticals Inc. (LBRX): Strong Open, Schizophrenia Biotech Finds Early Momentum

By IPO Boutique

  • LB Pharmaceuticals (LBRX) priced an upsized IPO of 19.0 million shares at the midpoint of the range, $15.00. Shares opened at $19.00, delivering a +26.7% gain at first trade.
  • Existing shareholders in previous rounds were likely anchoring the stock and providing stabilization in its debut.
  • We expect short-term trading to follow the broader biotech sector trend, with catalysts tied directly to clinical and regulatory developments.

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