Daily BriefsHealthcare

Daily Brief Health Care: Torii Pharmaceutical, Jiangsu Hengrui Medicine, Biogen Inc, Hogy Medical, Aptamer Group, Telomir Pharmaceuticals, HCA Healthcare, Inc. , Avantor and more

In today’s briefing:

  • [JAPAN M&A] Shionogi (4507) Bids for Torii Pharma (4551) – Split Price Deal on Weak Transparency
  • Torii Pharma (4551 JP): Shionogi & Co (4507 JP) JPY6,350 Tender Offer
  • Pre-IPO Jiangsu Hengrui Medicine H Share Listing (PHIP Updates) – Some Points Worth the Attention
  • Biogen, Inc. – Steady as She Goes as the Ship Continues to Turn Slowly
  • Hogy Medical (3593 JP): Premium Kits Carry It Through, Recovery in Sight in H2FY26
  • Hybridan Small Cap Feast: 30/04/2025
  • Jiangsu Hengrui Pharma A/H Listing – PHIP Updates and Updated Thoughts on A/H Premium
  • TELO: Tests Show Positive Cell Damage Repair Ability
  • HCA Healthcare: An Insight Into The Labor Market Dynamics & Wage Trends & Vital Factors Driving Growth!
  • Avantor’s Bioprocessing Boom: Is This Billion Dollar Platform The Key To Outsized Growth?


[JAPAN M&A] Shionogi (4507) Bids for Torii Pharma (4551) – Split Price Deal on Weak Transparency

By Travis Lundy

  • Today after the close, Shionogi & Co (4507 JP) and Torii Pharmaceutical (4551 JP) announced an agreed deal whereby Shionogi would launch a Tender Offer to take over Torii.
  • Torii Pharmaceutical shares rallied sharply after earnings so the actual TOB Price of ¥6,350/share is not a particularly high premium vs undisturbed. Valuation transparency is limited. Synergies are not included.
  • But the price is an ATH, the company is heavily de-levered (so a 23% premium to undisturbed is decent) and the minimum threshold is not high.

Torii Pharma (4551 JP): Shionogi & Co (4507 JP) JPY6,350 Tender Offer

By Arun George

  • Torii Pharmaceutical (4551 JP) has recommended a tender offer from Shionogi & Co (4507 JP) at JPY6,350 per share, a 13.8% premium to the last close.
  • Despite the lack of an auction and low takeover premium, the offer is attractive compared to historical trading ranges and peer multiples and represents an all-time high. 
  • Japan Tobacco (2914 JP), the controlling shareholder, has provided an irrevocable. The required minority acceptance rate is achievable as the offer is reasonable.  

Pre-IPO Jiangsu Hengrui Medicine H Share Listing (PHIP Updates) – Some Points Worth the Attention

By Xinyao (Criss) Wang

  • Hengrui’s high growth in 2024/25Q1 mainly relies on the realization of BD cooperation. The short-term performance improvement cannot conceal the long-term pressure. The turning point of endogenous growth hasn’t arrived.
  • Hengrui would continue to be affected by VBP. The generic drug business is “outdated”, whose valuation contribution is negligible. The BD model will lead to significant fluctuations in performance.
  • Our forecast is net profit YoY growth in 2025-2027 would fall back to 15-20%. Hengrui’s valuation should be lower than that of BeiGene and Hansoh in Hong Kong stock market.

Biogen, Inc. – Steady as She Goes as the Ship Continues to Turn Slowly

By Water Tower Research

  • 2025 guidance reaffirmed despite better-than- expected 1Q25 revenues.
  • Despite beating expectations with a 6% Y/Y growth in reported revenues to $2.4B (8% Y/Y growth on a constant currency basis) for 1Q25, Biogen nevertheless maintained its full year revenue guidance for a mid-single digit drop in constant currency (CC) revenues, which will make it the sixth consecutive year of revenue decline for the company.
  • Although Biogen lowered its 2025 non-GAAP EPS guidance range to $14.50-$15.50 from the previous range of $15.25- $16.25, this negative revision is not a sign of unanticipated business deterioration. 

Hogy Medical (3593 JP): Premium Kits Carry It Through, Recovery in Sight in H2FY26

By Tina Banerjee

  • Hogy Medical (3593 JP) reported flat sales of ¥39.1B in FY25. However, sales from Premium kits rose 18%. Surgical kits category contributed 66% of total revenue.
  • Higher costs dented operating margin by 100 bps while net profit declined 46% YoY to ¥1.5B due to higher tax outgo.
  • The company guided FY26 sales to grow 7% to ¥41.8B, with profits also expected to witness mid to high single digit growth.

Hybridan Small Cap Feast: 30/04/2025

By Hybridan

  • Aptamer Group o.325p £6.47m (APTA.L) The developer of next-generation synthetic binders delivering innovation to the life science industry has entered into a global licensing agreement with the University of Glasgow.
  • The Agreement is for the commercial use of its Optimer binders as vaccine adjuvants in the swine health sector.
  • The University will lead product development; commercialisation is anticipated within the next 12 months.

Jiangsu Hengrui Pharma A/H Listing – PHIP Updates and Updated Thoughts on A/H Premium

By Sumeet Singh

  • Jiangsu Hengrui Medicine (600276 CH) (JHP), a China-based pharmaceutical company, aims to raise around US$2bn in its H-share listing.
  • JHP has been ranked as one of the global Top 50 pharmaceutical companies by Pharm Exec for six consecutive years since 2019.
  • We have looked at the past performance and other dynamics in our previous note. In this note, we talk about the updates and provide our thoughts on the A/H premium.

TELO: Tests Show Positive Cell Damage Repair Ability

By Zacks Small Cap Research

  • Telomir Pharmaceuticals is a preclinical stage company focused on the science of lengthening telomere caps, which the company believes will extend human lifespans and improve quality of life as people age.
  • The company released test results that showed Telomir-1 reverses multiple signs of cellular decline across human cell lines.
  • This provides a foundation for the company to pursue treatments of autism and spasmodic dysphonia.

HCA Healthcare: An Insight Into The Labor Market Dynamics & Wage Trends & Vital Factors Driving Growth!

By Baptista Research

  • HCA Healthcare’s recent earnings call for Q1 2025 presents a nuanced picture of the company’s performance and strategic position.
  • The company recorded strong financial results based on consistent volume growth, an improved payer mix, and increased operating margin.
  • Diluted earnings per share also saw a notable 20% increase, reaching $6.45.

Avantor’s Bioprocessing Boom: Is This Billion Dollar Platform The Key To Outsized Growth?

By Baptista Research

  • Avantor’s first-quarter 2025 earnings results reveal both challenges and strategic initiatives that frame a complex investment landscape for the company.
  • Avantor reported an organic revenue decline of 2% year-over-year, signaling underperformance primarily within its Lab Solutions segment.
  • Despite this, the company managed to maintain an adjusted EBITDA margin of 17%, a 20 basis point increase from the prior year.

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